UGENE

by Uniprov53.1

Last updated Aug 27, 2026

UGENE is a free open-source bioinformatics software for Windows, macOS, and Linux.

Install with winget

$ winget install --id Unipro.UGENE --exact --version 53.1

Run in Command Prompt, PowerShell, or Windows Terminal. Prompts for any agreements.

Silent install command for UGENE

UGENE uses EXE (NSIS). The silent install switches are /S.

One-line silent install (x64, machine scope)

ugene-53.1-win-x86-64.exe /S

See the full silent install reference for UGENE →

Built by Pckgr

For Intune admins

Stop chasing app updates. Pckgr patches them for you.

Automated application patching for Microsoft Intune. Pckgr keeps a curated library of 1,000+ apps continuously up-to-date in your tenant via Microsoft Graph - no manual repackaging, no chasing vendor sites.

Start free 30-day trial

From $49/month. No credit card required.

Not on Intune? Pckgr RMM deploys and patches apps like this one on any Windows fleet. Free for up to 5 devices.

Installers · v53.1

Architecture	Type	Scope	Install	Download
x64	EXE NSIS	machine		Direct

Copy a command tailored to that specific architecture, type, and scope - useful when winget would otherwise pick a different default.

Security

No known CVEs for UGENE.

Coverage is best-effort and depends on a winget package mapping to an NVD CPE entry. Absence here is not a guarantee of safety.

Related apps

PowerShellMicrosoft Corporation
Microsoft.PowerShellv7.6.9.0
PowerShell is a cross-platform task automation solution made up of a command-line shell, a scripting language, and a configuration management framework. PowerShell runs on Windows, Linux, and macOS.
Node.js (LTS)Node.js Foundation
OpenJS.NodeJS.LTSv26.13.0
Run JavaScript Everywhere
YouTube Music Desktop AppNovusTheory
Ytmdesktop.Ytmdesktopv2.0.12
A unofficial player for YouTube Music on desktop
GitHub CLIGitHub, Inc.
GitHub.cliv2.103.3
Take GitHub to the command line
ActivityWatchActivityWatch Contributors
ActivityWatch.ActivityWatchv0.14.1
ActivityWatch is an app that automatically tracks how you spend time on your devices.
ArroxyAntonio Orionus
AntonioOrionus.Arroxyv0.7.4
Free, open-source video downloader for YouTube and 2000+ other sites. Save videos, playlists, channels and audio in up to 8K HDR, and sign in through the built-in browser for private or members-only videos. No ads.

More from Unipro or browse bioinformatics, cpp, cross-platform.

Frequently asked questions

How do I install UGENE on Windows?

Open Windows Terminal, PowerShell, or Command Prompt and run: winget install --id Unipro.UGENE --exact --version 53.1. winget downloads the installer from Unipro and runs it. Requires Windows 10 (1809+) or Windows 11.

How do I install UGENE silently for unattended deployment?

Add --silent and accept the agreements upfront: winget install --id Unipro.UGENE --exact 53.1 --silent --accept-package-agreements --accept-source-agreements. This is the variant Intune, Configuration Manager, and other deployment tools should use.

What are the silent install switches for UGENE?

UGENE uses EXE (NSIS). Run the downloaded installer with: ugene-53.1-win-x86-64.exe /S. The silent switches are /S.

How do I uninstall UGENE via winget?

Run: winget uninstall --id Unipro.UGENE --exact. Add --silent for unattended uninstalls. winget will use the registered uninstaller from UGENE's Apps & Features entry.

Is UGENE free?

UGENE is distributed under GPL-2.0. Refer to the publisher (https://ugene.net/) for the full license terms - Wingetly itself does not charge for installation.

Does UGENE work on Windows 10?

Yes, as long as your Windows 10 build supports winget (1809 or newer). winget ships with App Installer on Windows 10/11 and pulls UGENE directly from the publisher.

How do I keep UGENE up to date?

Run winget upgrade --id Unipro.UGENE --exact, or winget upgrade --all to update everything winget tracks. We index 4 versions of UGENE from microsoft/winget-pkgs.

Recent versions

53.1latest
52.1
52.0
51.0